San Antonio Highways

Within the city, interstate highways divide the metropolis into several areas. I-35 runs an S-shaped curve through the city from northeast to southwest, skirting the downtown. This mega-highway travels to Laredo at its southern end and Duluth, Minnesota in its northern regions.

I-10, which originates in Los Angeles, runs northwest to downtown before taking an easterly turn toward its final stop in Jacksonville, Florida. And I-37 defines the eastern boundary of downtown before veering off to the south and down to the coastal city of Corpus Christi. (To further confuse drivers, I-37 and I-35 are the same highway in the downtown region.)

Five U.S. highways also call on the Alamo City:

• US 281, which originates in Hansboro, North Dakota, swings through the city near the San Antonio International Airport on its way south to McAllen, Texas.
• US 90, also from Jacksonville, Florida, overlaps with I-10 as it approaches the city from the east and crosses the city before branching off and heading west to Van Horn, Texas.
• US 87, originating in Raton, New Mexico, also overlaps with I-10 in the western portion of the city before branching off to the east and making its way south to Port Lavaca, Texas.
• US 181 (not to be confused with US 281) originates in San Antonio and travels to Corpus Christi via Beeville.
• US 81 also originates in San Antonio and travels to Laredo , overlapping with I-35.
  

San Antonio is also circled by two loops: Loop 410 (the inside loop) and Loop 1604, lying on the fringes of the region.

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